After spinal cord injury (SCI), there aren’t many interventions we have available that actually make a difference. Hypertensive therapy is relatively safe and easy to implement but not without risk. 

In this CODA Podcast (recorded at CODA2022) Tessa Garside discusses the pros and cons, how this is managed practically and what the future may hold in this area.

Summary

After spinal cord injury (SCI), there aren’t many interventions we have available that actually make a difference. 

Augmenting blood pressure to increase spinal cord perfusion pressure is an attractive concept that may improve neurological outcomes following SCI. We know that hypotension can make SCI worse. Clinical studies looking at blood pressure augmentation are mostly old, retrospective and flawed in various ways. 

Aiming for a MAP of > 85 for 5-7 days is recommended by guidelines but why this pressure and duration are good questions.

Hypertensive therapy is relatively safe and easy to implement but not without risk. 

Tessa Garside discusses the pros and cons, how this is managed practically and what the future may hold in this area.

Slides

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