- 10 mg vitamin K IV
- Weight based dose prothrombin complex concentrate. FFP is alternative.
- Anti-platelet agents can potentially increase the risk and severity of aneurysm re-rupture, as well as neurosurgical complications.
- Platelet transfusion is recommended for patients with aspirin- or adenosine diphosphate (ADP) inhibitor-associated SAH who will undergo a neurosurgical procedure.
- Platelet transfusion is not recommended if no neurosurgical procedure is planned.
- The risk–benefit ratio of anti-platelet therapy reversal using other hemostatic agents such as desmopressin (DDAVP) should be considered for individual patients.
- Idarucizumab (Praxbind) 5g IV
- Andexanet alfa (AndexXa) 200 mg (see here for more)